Paulus M Verschuren

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Basal and hormone-stimulated lipolysis of adipose tissue was measured at successive stages during the development of fish oil-induced yellow fat disease in rats. Changes of lipolytic activity at an early stage of yellow fat disease were not seen. There was a significant increase of basal lipolysis and a decrease of stimulated lipolysis when many fat cells(More)
Saturated and trans-fatty acids raise total cholesterol and LDL-cholesterol and are known to increase the risk of CHD, while dietary unsaturated fatty acids play important roles in maintaining cardiovascular health. Replacing saturated fats with unsaturated fats in the diet often involves many complex dietary changes. Modifying the composition of foods high(More)
In this study di-n-butyltindichloride (DBTC) was found to inhibit alpha-ketoacid-stimulated response of rat liver mitochondria to the addition of ADP and the uncoupler carbonyl cyanide p-trifluoromethoxyphenyl hydrazone (FCCP). The alpha-ketoglutarate oxidation was already inhibited at a level of 0.8 nmol DBTC/mg protein. When succinate was used as(More)
The vitamin E requirement of rabbits fed a semi-synthetic diet containing high amounts of fish oil was studied. Three groups of 5 rabbits were fed fish oil diets containing, respectively, 50, 100 and 500 mg/kg vitamin E. Moreover diet palatability was evaluated by using different levels of grass meal: 0.5, 1 and 2%, respectively. Incorporation of 1% grass(More)
In rats with "stage S/E" yellow fat disease an injection of colloidal carbon resulted in a marked reduction in the number of circulating platelets. The death rate of rats with experimental Listeria monocytogenes infection, the number of bacteria in their spleens and the decrease of bacteria in their spleens on the days after infection were the same in rats(More)
Yellow fat disease was induced in young rats given a vitamin E-deficient diet supplemented with 15% fish oil. The changes in adipose tissue of this oil-induced disorder were different from those of natural yellow fat disease in horse, pig and mink. In the natural disease all fat depots had the early stage of yellow fat disease with interstitial(More)
The relationship between dietary fat consumption and the incidence of breast cancer, if any, needs to be quantified so that dietary guidelines can be issued for the prevention of breast cancer. Frequently, only two widely different dietary fat levels, often differing in essential fatty acid content, have been compared in animal models. Moreover, the latent(More)
The nutritional properties of jojoba oil (JO) were examined in a 4-wk feeding study of rats fed a diet with JO at dose levels of 2.2, 4.5 and 9%, supplemented with a conventional fat up to 18%. General health, survival and food intake were not adversely affected. Body-weight gains showed a dose-related decline, which amounted to 20% of the body weight in(More)