Paulo Roberto Benchimol-Barbosa

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BACKGROUND The electrocardiogram (ECG) of the athlete displays particular characteristics as a consequence of both electrophysiological and autonomic remodeling of the heart that follows continued physical training. However, doubts persist on how these changes directly interact during ventricular activation and repolarization ultimately affecting surface(More)
Chagas' disease is complex immune-mediated disease originated after Trypanosome cruzi transmission, and a major cause of heart failure in Latin American continent. Auto-antibodies directed to type 2 muscarinic parasympathetic (M2) receptors seem to play key roles on the pathogenesis of heart disease, in particular in the impairment of the cardiac autonomic(More)
BACKGROUND Deceleration capacity (DC) of heart rate is a measure of cardiac vagal modulation. This study introduced a DC adaptation (Modified Index) that measured the velocity of change in the phase-rectified signal averaging curve, and assessed its ability to discriminate athletes from controls. MATERIALS AND METHODS The Modified Index was compared to(More)
This paper proposes a technique to improve the quality of high-resolution electrocardiogram by weighting the coherent average of beats by a function of the energy of the corrupting myoelectric noise, prior to subsequent detection of ventricular late potentials. The results obtained with 20 patients indicate the method requires fewer beats than conventional(More)
Some thrombophilias and severe preeclampsia may increase the risk for preterm deliveries and fetal death due to placental insufficiency. Our objective was to evaluate clinical and laboratory data as predictors of preeclampsia in a population of mothers with 3rd trimester fetal losses or preterm deliveries. In a longitudinal retrospective study, 54(More)
BACKGROUND The athlete's heart represents a reversible structural and functional adaptations of myocardial tissue developed through physical conditioning. Surface electrocardiogram (ECG) has the capability to detect myocardial hypertrophy but has limited performance in monitoring physical conditioning-induced myocardial remodeling. The aim of this study was(More)
Ventricular late potentials (VLP) are electrical signals detected at the terminal region of the ventricular activation on surface ECG and often correlated to regions of fragmented electrical conduction in subjacent damaged myocardium. Intraventricular electrical transients (IVET) arisen from myocardial infarction scars may influence VLP identification(More)
Time-frequency maps of signal-averaged electrocardiogram based on a short time Fourier transform (STFT) technique analysis was employed to assess the presence of high frequency electrical transients (turbulence) and arrhythmia risk assessment. The optimal configuration set of STFT variables aiming at risk stratification for sustained monomorphic ventricular(More)
The 24-h heart rate variability and QT-interval adaptation was investigated in perinatally HIV-infected preschool children classified according to immunological status in order to assess autonomic function at early stages of infection. Thirty-five perinatally HIV-infected and clinically stable children (4.8 +/- 0.3 years) were enrolled after approval of the(More)