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PURPOSE The consumption of a high level of dietary extract from blackcurrant pomace rich in polyphenols was hypothesised to exert beneficial effects on the serum lipid profile, the markers of insulin resistance and the antioxidant status of the host without negative changes in the intestinal tract. METHODS This hypothesis was tested on 20 male New Zealand(More)
In the study, the possible effect of sodium valproate (NaVP) on urethane-induced lung tumors in mice has been evaluated. BALB/c mice (n = 120; 4-6 weeks old, both sexes) were used in the following groups: 1) urethane-treated, 2) urethane-NaVP-treated, 3) only NaVP-treated, 4) control. In the same groups, castrated male mice (n = 48) were investigated.(More)
Sodium-dependent Cl(-)/HCO3 (-) exchanger acts as a chloride (Cl(-)) efflux in lymphocytes. Its functional characterization had been described when Cl(-) efflux was measured upon substituting extracellular sodium (Na(+)) by N-methyl-D-glucamine (NMDG). For Na(+) and Cl(-) substitution, we have used D-mannitol or NMDG. Thymocytes of male Wistar rats aged 7-9(More)
In the present study, the possible effect of sodium valproate (NaVP) on urethane-induced lung tumors in female mice has been evaluated. BALB/c mice (n = 60; 4-6 weeks old, females) were used in the following groups: (1) urethane-treated; (2) urethane-NaVP-treated; (3) only NaVP-treated; (4) control. In the same groups, ovariectomized female mice (n = 60)(More)
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