Pauline van der Wielen

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Explanted voice prostheses obtained from 5 patients at the time of prosthesis replacement were consistently colonized by yeast, in particular Candida albicans. A simple, reproducible, in vitro model of C. albicans adherence to saliva-coated voice prosthesis silicone was developed. Whole saliva promoted adherence of C. albicans to silicone in a(More)
Interactions between Candida albicans, saliva and saliva-coated oral surfaces are initial events in the colonization of the oral cavity by this commensal yeast, which can cause oral diseases such as candidiasis and denture stomatitis. Candida albicans also colonizes silicone voice prostheses, and the microbial biofilm formed can impair valve function,(More)
In an in vitro study on six knees from cadavers, the effect of bone-patellar tendon-bone graft twist on anterior knee laxity was measured at different knee flexion angles. A motion and loading rig was used to prescribe the flexion angle, to restrain axial rotation, and to apply 100 N anterior force to the tibia. Roentgen stereophotogrammetric analysis was(More)
OBJECTIVES Candida albicans attaches to oral surfaces via a number of mechanisms including adherence mediated by salivary components adsorbed to the C. albicans cell surface. Our goal was to identify the salivary molecules involved. MATERIALS AND METHODS Biotinylated salivary polypeptides that were bound by C. albicans were detected in extracts from(More)
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