Pauline T Merrill

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OBJECTIVE To assess the results of surgical excision of subfoveal choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD). DESIGN Retrospective, interventional, noncomparative case series. PARTICIPANTS AND INTERVENTION Sixty-four consecutive patients undergoing surgical removal of AMD-related subfoveal CNV were(More)
BACKGROUND Non-infectious uveitis is a potentially sight-threatening ocular disorder caused by chronic inflammation and its complications. Therapeutic success is limited by systemic adverse effects associated with long-term corticosteroid and immunomodulator use if topical medication is not sufficient to control the inflammation. We aimed to assess the(More)
BACKGROUND AND OBJECTIVE Subfoveal neovascular membranes are usually located either in the subsensory retinal space or below the retinal pigment epithelium (RPE). This article describes the clinical and histopathologic features of subfoveal membranes with both subretinal and sub-RPE components (combined membranes). PATIENTS AND METHODS Six surgically(More)
PURPOSE To report our experience with perfluoro-N-octane (PFO) in the surgical management of complicated retinal detachments due to proliferative diabetic retinopathy. METHODS Retrospective review of 18 consecutive eyes of 18 patients with tractional or combined tractional and rhegmatogenous retinal detachments due to severe proliferative diabetic(More)
PURPOSE To report a case of cytomegalovirus acute retinal necrosis after a sub-Tenon injection of triamcinolone acetonide in an immunocompetent patient. METHODS A 77-year-old man received a sub-Tenon injection of triamcinolone acetonide for treatment of iritis unresponsive to topical steroids. He subsequently developed unilateral acute retinal necrosis.(More)
AIM Vitreoretinal lymphoma is a diffuse large B cell non-Hodgkin lymphoma. Targeting malignant cells with rituximab is being used increasingly as local chemotherapy, but information on this treatment is scant. We aimed to describe current therapeutic approaches, as well as responses to and complications of, intravitreal rituximab in patients with(More)
PURPOSE To assess the prevalence of hypotony in patients with severe forms of uveitis. METHODS The Multicenter Uveitis Steroid Treatment (MUST) Trial, a randomized study, enrolled 255 patients. Patients with hypotony at the baseline visit were identified. RESULTS Twenty (8.3%) of 240 patients with sufficient data had hypotony. Hypotony was more common(More)
A 73-year-old Hispanic man presented with a gradual decrease in visual acuity in the left eye over 3 weeks time. He had longstanding type 2 diabetes mellitus, proliferative diabetic retinopathy, and clinically significant diabetic macular edema for which he has had both panretinal photocoagulation and focal macular laser. Cataract surgery had been performed(More)
The diabetic macular edema (DME) treatment paradigm has evolved as the understanding of the disease pathology has grown. Since 2012, four pharmacotherapies have been approved by the U.S. Food and Drug Administration for the treatment of DME. First-line treatment of DME with anti-vascular endothelial growth factor [VEGF] agents has become the gold standard;(More)
BACKGROUND/PURPOSE To describe a case of bilateral macular edema appearing after treatment with rituximab. METHODS This is a case report describing macular edema after rituximab infusions. The information was collected retrospectively through chart review. RESULTS A 53-year-old patient known for IgG4-related disease of the face and sinuses presented(More)