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  • Juan Beauquis, Paulina Roig, Françoise Homo-Delarche, Alejandro Federico De Nicola, Flavia Saravia
  • Biology, Medicine
  • The European journal of neuroscience
  • 2006 (First Published: 1 March 2006)
  • Cerebral dysfunctions, including a high incidence of depression, are common findings in human type 1 diabetes mellitus. An association between depression and defective hippocampal neurogenesis hasContinue Reading
  • Laura Ivonne Garay, María Claudia González Deniselle, Analía E. Lima, Paulina Roig, Alejandro F. De Nicola
  • Medicine
  • The Journal of Steroid Biochemistry and Molecular…
  • 2007 (First Published: 1 November 2007)
  • The spinal cord is a target of progesterone (PROG), as demonstrated by the expression of intracellular and membrane PROG receptors and by its myelinating and neuroprotective effects in trauma andContinue Reading
  • Florencia Labombarda, Susana Laura González, Analía E. Lima, Paulina Roig, Alejandro F. De Nicola
  • Medicine, Biology
  • Experimental Neurology
  • 2011 (First Published: 1 September 2011)
  • Reactive gliosis, demyelination and proliferation of NG2+ oligodendrocyte precursor cells (OPC) are common responses to spinal cord injury (SCI). We previously reported that short-term progesteroneContinue Reading
  • Florencia Labombarda, Susana Laura González, +4 authors Alejandro Federico De Nicola
  • Biology, Medicine
  • Glia
  • 2009 (First Published: 1 June 2009)
  • Progesterone is emerging as a myelinizing factor for central nervous system injury. Successful remyelination requires proliferation and differentiation of oligodendrocyte precursor cells (OPC) intoContinue Reading
  • Juan Beauquis, Paulina Roig, Alejandro Federico De Nicola, Flavia Saravia
  • Medicine, Biology
  • PloS one
  • 2010 (First Published: 15 November 2010)
  • BACKGROUND Several brain disturbances have been described in association to type 1 diabetes in humans. In animal models, hippocampal pathological changes were reported together with cognitiveContinue Reading
  • Luciana Pietranera, Flavia Saravia, Maria Claudia Gonzalez Deniselle, Paulina Roig, Analía E. Lima, Alejandro Federico De Nicola
  • Medicine
  • Journal of neuroendocrinology
  • 2006 (First Published: 1 June 2006)
  • Hippocampal neuropathology is a recognised feature of the brain in spontaneously hypertensive rats (SHR), but similar studies are lacking in another model of hypertension, theContinue Reading
    BACKGROUND Peripheral nerve injury-evoked neuropathic pain still remains a therapeutic challenge. Recent studies support the notion that progesterone, a neuroactive steroid, may offer a promisingContinue Reading