• Publications
  • Influence
Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells.
The forkhead box n1 (Foxn1) transcription factor is essential for thymic organogenesis during embryonic development; however, a functional role of Foxn1 in the postnatal thymus is less wellExpand
  • 96
  • 5
Structure and promoter characterization of aldo-keto reductase family 1 B10 gene.
Aldo-keto reductase family 1 member B10 (AKR1B10) is overexpressed in human hepatocellular carcinoma, lung squamous carcinoma, and lung adenocarcinoma in smokers. Our recent studies have showed thatExpand
  • 22
  • 2
Protection against Staphylococcus aureus bacteremia-induced mortality depends on ILC2s and eosinophils.
The dysregulated, unbalanced immune response of sepsis results in a mortality exceeding 20%, yet recent findings by our group indicate that patients with allergic, type 2-mediated immune diseases areExpand
  • 10
  • 2
  • Open Access
Serum Amyloid A Facilitates Early Lesion Development in Ldlr−/− Mice
Background Atherosclerosis is a chronic inflammatory disorder, and several studies have demonstrated a positive association between plasma serum amyloid A (SAA) levels and cardiovascular diseaseExpand
  • 21
  • 1
  • Open Access
Y Chromosome STR Haplotypes and Allele Frequencies in Illinois Caucasian, African American, and Hispanic Males
POPULATION: Population: Illinois Caucasian (n=117), Illinois African American (n=218), and Illinois Hispanic (n=68).
  • 4
  • 1
Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression.
Acrolein is a highly reactive alpha,beta-unsaturated aldehyde produced endogenously during lipid peroxidation and naturally distributed pervasively in living environments, posing serious threats toExpand
  • 37
  • Open Access
Role of aldo-keto reductases in development of prostate and breast cancer.
Aldo-keto reductase (AKR) is a super gene family, consisting of fourteen families and more than 40 members overall. These proteins have been well known as metabolic enzymes of carbonyls, but recentExpand
  • 33
  • Open Access
Serum amyloid A and atherosclerosis
Purpose of review Atherosclerosis is a chronic inflammation associated with increased expression of the acute phase isoforms of serum amyloid A (SAA) and in humans is a plasma biomarker for futureExpand
  • 26
Apolipoprotein A-I Protection Against Atherosclerosis Is Dependent on Genetic Background
Objective—Inbred mouse strains have different susceptibilities to experimental atherosclerosis. The C57BL/6 strain is among the most sensitive and has, therefore, been the most widely used inExpand
  • 17
  • Open Access
Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii.
We created and tested multi-epitope DNA or protein vaccines with TLR4 ligand emulsion adjuvant (gluco glucopyranosyl lipid adjuvant in a stable emulsion [GLA-SE]) for their ability to protect againstExpand
  • 24
  • Open Access