Paulette A. Krishack
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Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells.
The forkhead box n1 (Foxn1) transcription factor is essential for thymic organogenesis during embryonic development; however, a functional role of Foxn1 in the postnatal thymus is less well… Expand
Structure and promoter characterization of aldo-keto reductase family 1 B10 gene.
Aldo-keto reductase family 1 member B10 (AKR1B10) is overexpressed in human hepatocellular carcinoma, lung squamous carcinoma, and lung adenocarcinoma in smokers. Our recent studies have showed that… Expand
Protection against Staphylococcus aureus bacteremia-induced mortality depends on ILC2s and eosinophils.
The dysregulated, unbalanced immune response of sepsis results in a mortality exceeding 20%, yet recent findings by our group indicate that patients with allergic, type 2-mediated immune diseases are… Expand
Serum Amyloid A Facilitates Early Lesion Development in Ldlr−/− Mice
- Paulette A. Krishack, Clarissa V Bhanvadia, +4 authors C. Reardon
- Journal of the American Heart Association
- 1 July 2015
Background Atherosclerosis is a chronic inflammatory disorder, and several studies have demonstrated a positive association between plasma serum amyloid A (SAA) levels and cardiovascular disease… Expand
Y Chromosome STR Haplotypes and Allele Frequencies in Illinois Caucasian, African American, and Hispanic Males
POPULATION: Population: Illinois Caucasian (n=117), Illinois African American (n=218), and Illinois Hispanic (n=68).
Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression.
- X. Zu, R. Yan, Sarah J. Robbins, Paulette A. Krishack, D. Liao, D. Cao
- Chemistry, Medicine
- Toxicological sciences : an official journal of…
- 1 June 2007
Acrolein is a highly reactive alpha,beta-unsaturated aldehyde produced endogenously during lipid peroxidation and naturally distributed pervasively in living environments, posing serious threats to… Expand
Role of aldo-keto reductases in development of prostate and breast cancer.
- Junfei Jin, Paulette A. Krishack, D. Cao
- Medicine, Biology
- Frontiers in bioscience : a journal and virtual…
- 1 September 2006
Aldo-keto reductase (AKR) is a super gene family, consisting of fourteen families and more than 40 members overall. These proteins have been well known as metabolic enzymes of carbonyls, but recent… Expand
Serum amyloid A and atherosclerosis
- G. Getz, Paulette A. Krishack, C. Reardon
- Biology, Medicine
- Current opinion in lipidology
- 1 October 2016
Purpose of review Atherosclerosis is a chronic inflammation associated with increased expression of the acute phase isoforms of serum amyloid A (SAA) and in humans is a plasma biomarker for future… Expand
Apolipoprotein A-I Protection Against Atherosclerosis Is Dependent on Genetic Background
- T. J. Sontag, Paulette A. Krishack, J. Lukens, Clarissa V Bhanvadia, G. Getz, C. Reardon
- Biology, Medicine
- Arteriosclerosis, thrombosis, and vascular…
- 1 February 2014
Objective—Inbred mouse strains have different susceptibilities to experimental atherosclerosis. The C57BL/6 strain is among the most sensitive and has, therefore, been the most widely used in… Expand
Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii.
We created and tested multi-epitope DNA or protein vaccines with TLR4 ligand emulsion adjuvant (gluco glucopyranosyl lipid adjuvant in a stable emulsion [GLA-SE]) for their ability to protect against… Expand