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Improved equations estimating GFR in children with chronic kidney disease using an immunonephelometric determination of cystatin C
The Chronic Kidney Disease in Children study is a cohort of about 600 children with chronic kidney disease (CKD) in the United States and Canada. The independent variable for our observations was aExpand
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Estimating Kidney Function in HIV-Infected Adults in Kenya: Comparison to a Direct Measure of Glomerular Filtration Rate by Iohexol Clearance
Background More than two-thirds of the world's HIV-positive individuals live in sub-Saharan Africa, where genetic susceptibility to kidney disease is high and resources for kidney disease screeningExpand
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Recalibration of cystatin C using standardized material in Siemens nephelometers
Background Cystatin C is a key GFR biomarker. Recently, Siemens recalibrated the assay based on certified reference material ERM-DA471/IFCC. The NIH-funded longitudinal chronic kidney disease inExpand
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Rapid assessment of renal reserve in young adults by cystatin C
Abstract Background. The kidney can increase glomerular filtration rate (GFR) in response to a protein load (renal reserve). In a pilot study of healthy young adults we examined renal reserve usingExpand
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Renal Response to a Protein Load in Healthy Young Adults as Determined by Iohexol Infusion Clearance, Cimetidine-Inhibited Creatinine Clearance, and Cystatin C Estimated Glomerular Filtration Rate.
OBJECTIVE Renal reserve (RR) measures the increase in glomerular filtration rate (GFR) in response to a protein load; lack of RR could indicate subclinical kidney disease but such a test is notExpand
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Racial Adjustment Adversely Affects Glomerular Filtration Estimates in African Americans Living with HIV
Background: The creatinine-based CKD EPI equation is the most widely used method to estimate glomerular filtration rate (eGFRcr) in clinical practice. The eGFRcr adjusts for sex, age, and race (BlackExpand
Cross-sectional and longitudinal performance of creatinine- and cystatin C-based estimating equations relative to exogenously measured glomerular filtration rate in HIV-positive and HIV-negative
BACKGROUND Reliable estimates of glomerular filtration rate (GFR) are important in the clinical management of HIV-positive patients. Data on the performance of widely used estimating equations (eGFR)Expand
Cross-Sectional and Longitudinal Performance of Creatinine- and Cystatin C-Based Estimating Equations Relative to Exogenously Measured Glomerular Filtration Rate in HIV-Positive and HIV-Negative
BACKGROUND Reliable estimates of glomerular filtration rate (GFR) are important in the clinical management of HIV-positive patients. Data on the performance of widely used estimating equations (eGFR)Expand