Paula Mychack

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Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by behavioural disorders that suggest abnormalities of emotional processing. Patients with the temporal variant of FTD (tvFTD) are particularly at risk for developing deficits in emotional processing secondary to atrophy in the amygdala, anterior temporal cortex (ATC) and orbital(More)
OBJECTIVE To evaluate the frequency and types of change in "self" seen in frontotemporal dementia (FTD) and to determine the relative involvement of the nondominant and dominant frontal and temporal brain regions in FTD patients with or without changes in a sense of self using neuropsychology tests and neuroimaging. BACKGROUND The self has been defined as(More)
BACKGROUND Efforts to characterize changes in social functioning in frontotemporal dementia (FTD) have failed to elicit clear dissociation between frontal and temporal variants of the disease based on behavioral measures. METHODS This study obtained premorbid and current first-degree relative ratings using an established measure of interpersonal(More)
BACKGROUND Frontotemporal dementia (FTD) is associated with a variety of cognitive and behavioral dysfunctions. Symptoms may be influenced by the relative involvement of the right versus the left hemisphere, with left-sided FTD manifesting language changes and right-sided FTD presenting with aggressive, antisocial, and other socially undesirable behaviors.(More)
OBJECTIVE The objectives of this study were to examine common patterns in the lives and artwork of five artistic savants previously described and to report on the clinical, neuropsychological, and neuroimaging findings from one newly diagnosed artistic savant. BACKGROUND The artistic savant syndrome has been recognized for centuries, although its(More)
Despite the realization that personality change is a core feature of frontotemporal dementia (FTD), little work has been performed using personality as a diagnostic tool for this disease. Likewise, personality change in Alzheimer's disease (AD) has long been recognized, but generally has not been used for diagnostic purposes. We introduce novel(More)
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