Paula Isono Fujiwara

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Stavudine (d4T) is now recommended at the dose of 30 mg twice daily for all adult and adolescent patients regardless of body weight.[A-III] After the publication of WHO's 2006 guidelines for HIV therapy in adults and adolescents, the WHO Guidelines Development Group (GDG) reviewed evidence for the use of stavudine (d4T) at reduced doses. Previously, the(More)
The creation of the present guidelines would not have been possible without the participation of numerous experts. This document was developed through an expert consultation process in which account was taken of current scientific evidence and the state of the art in the treatment of HIV infection. The primary focus was the context of resource-limited(More)
BACKGROUND Zimbabwe has been severely affected by the HIV/AIDS and tuberculosis epidemics, with an estimated 80% of tuberculosis patients being HIV infected. We set out to use annual population-mortality records from the cities of Harare and Bulawayo to describe trends and possible causes of mortality from 1979 to 2008. The specific objectives were to(More)
BACKGROUND As part of its policy to shift monitoring of antiretroviral therapy (ART) to primary health care (PHC) workers, the Ministry of Health of the Democratic Republic of Congo (DRC) tested the feasibility of using dried blood spots (DBS) for viral load (VL) quantification and genotypic drug resistance testing in off-site high-throughput laboratories.(More)
Background: As part of its policy to shift monitoring of antiretroviral therapy (ART) to primary health care (PHC) workers, the Ministry of Health of the Democratic Republic of Congo (DRC) tested the feasibility of using dried blood spots (DBS) for viral load (VL) quantification and genotypic drug resistance testing in off-site high-throughput laboratories.(More)
BACKGROUND The use of liquid medium (MGIT960) for tuberculosis (TB) diagnosis was recommended by WHO in 2007. However, there has been no evaluation of its effectiveness on clinically important outcomes. METHODS AND FINDINGS A pragmatic trial was carried out in a tertiary hospital and a secondary health care unit in Rio de Janeiro City, Brazil.(More)
Community involvement in tuberculosis care and prevention Towards partnerships for health Community involvement in tuberculosis care and prevention Towards partnerships for health Guiding principles and recommendations based on a WHO review Please send us feedback on this publication and share your experiences. It is anticipated that the recommendations in(More)
Cell-mediated immunity (CMI) in a population of 28 well-nourished, disease-free old-age individuals (65--103 years) was compared to that of healthy young adult controls (22--41 years) and the effects in vitro of thymosin fraction 5 (TF5) evaluated. The number of T cells (T cell rosettes, TCR) in the peripheral blood was the same as controls. However, there(More)
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