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PURPOSE To demonstrate the technical feasibility and precision of a navigated diffusion-weighted (DW) MR imaging method with interleaved echo-planar imaging and test its diagnostic sensitivity for detection of ischemic stroke. MATERIALS AND METHODS Apparent diffusion coefficient (ADC) measurements were performed in phantoms, and six healthy adult(More)
Linear approaches like the minimum-norm least-square algorithm show insufficient performance when it comes to estimating the activation time map on the surface of the heart from electrocardiographic (ECG) mapping data. Additional regularization has to be considered leading to a nonlinear problem formulation. The Gauss-Newton approach is one of the standard(More)
Finite Element Method (FEM) using 26-node isoparametric finite elements was applied for modeling saddle-shaped head coils used in Magnetic Resonance Imaging (MRI) generating linearly polarized radiofrequency (RF) pulses at 64 MHz. The human head was modeled from MR scans of a volunteer and additional information were taken from Atlas of Sectional Human(More)
An iterative algorithm based on a general regularization scheme for nonlinear ill-posed problems in Hilbert scales (method A) is applied to the magnetocardiographic inverse problem imaging the surface myocardial activation time map. This approach is compared to an algorithm using an optimization routine for nonlinear ill-posed problems based on Tikhonov's(More)
The authors describe a method for accurate in vivo multislice imaging of the active component of the B1 field which is based on a previously proposed method, which uses the signal intensity ratio of two images measured with different excitation angles, and a repetition time TR 5 > or = 5 T1. The new method essentially reduces repetition and scan time by(More)
The analytic solution of the harmonic downward continuation of the scalp potential field in an N-shell heterogeneous, but isotropic, spherical volume conductor model has been derived. The objective of this paper was to investigate the realization of a so-called "high-resolution electroencephalogram (EEG)": by enhancing the poor spatial resolution of EEG(More)
In clinical electrocardiography, the zero-potential is commonly defined by the Wilson central terminal. In the electrocardiographic forward and inverse problem, the zero-potential is often defined in a different way, e.g., by the sum of all node potentials yielding zero. This study presents relatively simple to implement techniques, which enable the(More)
A filter based on fuzzy logic for state estimation of a glucoregulatory system is presented. A published non-linear model for the dynamics of glucose and its hormonal control including a single glucose compartment, five insulin compartments and a glucagon compartment was used for simulation. The simulated data were corrupted by an additive white noise with(More)
In this paper we present a study of spline surface Laplacian (LP), linear estimation (LE) and analytical deblurring (AD) utilized to improve the spatial resolution of single trial EEG data. AD is a method to reconstruct the potential distribution on the cortical surface. The dependency of AD on the electrode grid size as well as the sensitivity to(More)
The fact that time-varying magnetic fields cause eddy currents in conductive objects is very well known. Switched magnetic gradient fields, used in echo planar imaging, were shown in the past to be able to elicit a stimulation process in peripheral nerves. We report about the distribution and values of induced current densities in the human torso, modeled(More)