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MICE which are homozygous for the niude gene (Flanagan, 1966) show thymic aplasia (Pantelouris, 1968) and because of the consequent lack of T-cell-mediated immunity (Kindred, 1971; Reed and Juilia, 1972), such nude mice will accept tumour heterotransplants. They have therefore been used for the maintenance of human tumours by passage (Giovanella an-id(More)
The malignant epithelial cells of nasopharyngeal carcinoma (NPC) and cells of lines derived form the lymphoid cells which infiltrate this tumour have been investigated cytogenetically. Chromosome spreads of lymphoblastoid cells of lines established from 7 different NPC biopsy specimens were examined after banding staining. Banding was also applied to the(More)
The bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase (RibD) represents a potential antibacterial drug target. The structure of recombinant Acinetobacter baumannii RibD is reported in orthorhombic and tetragonal crystal forms at 2.2 and 2.0 Å resolution, respectively. Comparisons with(More)
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