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We propose a novel method to obtain a part of an optimal non-relaxed integral solution for energy minimization problems with Potts interactions, known also as the minimal partition problem. The method empirically outperforms previous approaches like MQPBO and Kovtun's method in most of our test instances and especially in hard ones. As a starting point our(More)
The recent emergence of artemisinin-resistant Plasmodium falciparum malaria in western Cambodia could threaten prospects for malaria elimination. Identification of the genetic basis of resistance would provide tools for molecular surveillance, aiding efforts to contain resistance. Clinical trials of artesunate efficacy were conducted in Bangladesh, in(More)
We consider the NP-hard problem of MAP-inference for graphical models. We propose a polynomial time practically efficient algorithm for finding a part of its optimal solution. Specifically, our algorithm marks each label in each node of the considered graphical model either as (i) optimal, meaning that it belongs to all optimal solutions of the inference(More)
BACKGROUND The emergence of artemisinin-resistant Plasmodium falciparum in Southeast Asia threatens malaria treatment efficacy. Mutations in a kelch protein encoded on P. falciparum chromosome 13 (K13) have been associated with resistance in vitro and in field samples from Cambodia. METHODS P. falciparum infections from artesunate efficacy trials in(More)
OBJECTIVE Recent reports indicate that first cases of genuine artemisinin resistance have already emerged along the Thai-Cambodian border. The main objective of this trial was to track the potential emergence of artemisinin resistance in Bangladesh, which in terms of drug resistance forms a gateway to the Indian subcontinent. METHODS We conducted an(More)
The WHO has reported that RDT and microscopy-confirmed malaria cases have declined in recent years. However, it is still unclear if this reflects a real decrease in incidence in Bangladesh, as particularly the hilly and forested areas of the Chittagong Hill Tract (CHT) Districts report more than 80% of all cases and deaths. surveillance and epidemiological(More)
We present a novel variational approach to image restoration (e.g., denoising, inpainting, labeling) that enables us to complement established variational approaches with a histogram-based prior, enforcing closeness of the solution to some given empirical measure. By minimizing a single objective function, the approach utilizes simultaneously two quite(More)