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BACKGROUND Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a disease-by-disease analysis. No complete revision of global disease burden caused by risk factors has been done since a comparative risk assessment in 2000, and no previous analysis has assessed(More)
BACKGROUND Reliable and timely information on the leading causes of death in populations, and how these are changing, is a crucial input into health policy debates. In the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010), we aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with(More)
BACKGROUND Patients with major depressive disorder are found to show selective attention biases towards mood-congruent information. Although previous studies have identified various structural changes in the brains of these patients, it remains unclear whether the structural abnormalities are associated with these attention biases. In this study, we used(More)
BACKGROUND Text analysis of personal documents provides insight into the cognition of those who complete suicide. Many personal documents are digitalized and easily found on the Internet, which can be used to advance suicide research. AIMS (1) To examine the temporal relationships between posting intensity and language use to sketch the suicidal process(More)
BACKGROUND The fifth Millennium Development Goal (MDG 5) established the goal of a 75% reduction in the maternal mortality ratio (MMR; number of maternal deaths per 100,000 livebirths) between 1990 and 2015. We aimed to measure levels and track trends in maternal mortality, the key causes contributing to maternal death, and timing of maternal death with(More)
BACKGROUND The Millennium Declaration in 2000 brought special global attention to HIV, tuberculosis, and malaria through the formulation of Millennium Development Goal (MDG) 6. The Global Burden of Disease 2013 study provides a consistent and comprehensive approach to disease estimation for between 1990 and 2013, and an opportunity to assess whether(More)
BACKGROUND Adolescent suicidal ideation has found to predict suicidal behaviors and psychopathology in adulthood. Previous studies focused solely on the medical and environmental risk factors, which were insufficient to give a holistic picture of adolescent suicidality. OBJECTIVES To assess the role of affective and cognitive attributes in the(More)
BACKGROUND Despite increasing concern over the potential adverse effects of excessive internet use, especially in young people, there is some debate over its definition, magnitude and discriminant validity. AIMS To examine the prevalence of adolescents' internet addiction in Hong Kong, China; to test its differentiation from other correlates; and to(More)
OBJECTIVE To investigate the impact of the 2008 global economic crisis on international trends in suicide and to identify sex/age groups and countries most affected. DESIGN Time trend analysis comparing the actual number of suicides in 2009 with the number that would be expected based on trends before the crisis (2000-07). SETTING Suicide data from 54(More)
BACKGROUND Long-term mortality and the risk factors for premature death among patients with schizophrenia living in rural communities are unknown. AIMS To explore the 10-year mortality and its risk factors among patients with schizophrenia. METHOD We used data from a 10-year prospective follow-up study (1994-2004) of mortality among people with(More)