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OBJECTIVE To date no trial has focused on the treatment of adolescents with bulimia nervosa. The aim of this study was to compare the efficacy and cost-effectiveness of family therapy and cognitive behavior therapy (CBT) guided self-care in adolescents with bulimia nervosa or eating disorder not otherwise specified. METHOD Eighty-five adolescents with(More)
This paper proposes a method for measuring investor risk appetite based on the variation in the ratio of risk-neutral to subjective probabilities used by investors in evaluating possible future returns to an asset. Unlike other indicators advanced in the literature, our measure of market sentiment distinguishes risk appetite from risk aversion, and is(More)
The paper reviews psychological and social scientific research on lay attitudes to food risks. Many experts (scientists, food producers and public health advisors) regard public unease about food risks as excessive. This expert-lay discrepancy is often attributed to a 'knowledge deficit' among lay people. However, much research in psychology and sociology(More)
The use of open, Internet-based communications for business-to-business (B2B) interactions requires accountability for and acknowledgment of the actions of participants. Accountability and acknowledgment can be achieved by the systematic maintenance of an irrefutable audit trail to render the interaction non-repudiable. To safeguard the interests of each(More)
The wide variety of services and resources available over the Internet presents new opportunities to create value added, inter-organisational Composite Services (CSs) from multiple existing services. The resulting CS can involve close interaction among the constituent services of participating organisations. To preserve their autonomy and privacy, each(More)
OBJECTIVE To assess the cost-effectiveness of dabigatran etexilate, a new oral anticoagulant, versus warfarin and other alternatives for the prevention of stroke and systemic embolism in UK patients with atrial fibrillation (AF). METHODS A Markov model estimated the cost-effectiveness of dabigatran etexilate versus warfarin, aspirin or no therapy. Two(More)