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  • Cristian Matthias, Keith Branigan, +7 authors Paul R. Hoban
  • Biology, Medicine
  • Clinical cancer research : an official journal of…
  • 1998 (First Published: 1 October 1998)
  • We have examined the correlation of a frequent A/G polymorphism within exon 4 of the cyclin D1 gene (CCND1) with genetic susceptibility and clinical outcome in 384 patients with squamous cellContinue Reading
  • Tracy J Lovatt, Julie Alldersea, +5 authors Richard C. Strange
  • Biology, Medicine
  • Human mutation
  • 2005 (First Published: 1 April 2005)
  • Cutaneous basal cell carcinoma (BCC) risk is mediated by interactions between ultraviolet radiation (UVR) and host factors, including DNA repair efficiency. We investigated the association betweenContinue Reading
  • Nigel A. Hibberts, David J. W. Simpson, +4 authors William E Farrell
  • Biology, Medicine
  • Clinical cancer research : an official journal of…
  • 1999 (First Published: 1 August 1999)
  • Cyclin D1 plays an important role in the regulation of cell progression through G1 of the cell cycle and has been demonstrated to have oncogenic properties. Using RFLP-PCR, an A/G polymorphism withinContinue Reading
  • R. E. J. Howells, Christopher W. G. Redman, +7 authors Richard C. Strange
  • Biology, Medicine
  • Clinical cancer research : an official journal of…
  • 1998 (First Published: 1 October 1998)
  • Epithelial ovarian cancer is generally associated with a poor outcome, although the mechanisms that determine survival and progression-free interval (PFI) are unclear. Data from ovarian tumorsContinue Reading
  • R. E. J. Howells, Kalyan K Dhar, +4 authors Richard C. Strange
  • Medicine
  • International journal of gynecological cancer…
  • 2004 (First Published: 1 March 2004)
  • Ovarian cancer accounts for the majority of deaths from gynaecological malignancy, and polymorphisms in genes encoding the glutathione-S-transferase (GST) GSTP1 detoxifying enzymes may lead toContinue Reading
  • Paul R. Hoban, Rachel L. Cowen, +4 authors J. E. Heighway
  • Biology, Medicine
  • Journal of medical genetics
  • 1997 (First Published: 1 April 1997)
  • A 6 month old boy presented with bilateral Wilms' tumour. Cytogenetic analysis of the lymphocytes from the patient showed a de novo balanced translocation t(5;6)(q21;q21), which was also present inContinue Reading
  • Cristian Matthias, Volker Jahnke, +5 authors Richard C. Strange
  • Medicine
  • Cancer epidemiology, biomarkers & prevention : a…
  • 1999 (First Published: 1 September 1999)
  • GST, CYP, and CCND1 genotypes have been associated with outcome in several cancers. Accordingly, we have examined, in patients with one squamous cell carcinoma (SCC) of the head and neck,Continue Reading