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BACKGROUND Few cohort studies have evaluated the risk of mortality associated with long-term exposure to fine particulate matter [≤ 2.5 μm in aerodynamic diameter (PM(2.5))]. This is the first national-level cohort study to investigate these risks in Canada. OBJECTIVE We investigated the association between long-term exposure to ambient PM(2.5) and(More)
OBJECTIVE Recent studies suggest that chronic exposure to air pollution can promote the development of diabetes. However, whether this relationship actually translates into an increased risk of mortality attributable to diabetes is uncertain. RESEARCH DESIGN AND METHODS We evaluated the association between long-term exposure to ambient fine particulate(More)
BACKGROUND Few studies examining the associations between long-term exposure to ambient air pollution and mortality have considered multiple pollutants when assessing changes in exposure due to residential mobility during follow-up. OBJECTIVE We investigated associations between cause-specific mortality and ambient concentrations of fine particulate(More)
BACKGROUND Numerous studies have examined associations between air pollution and pregnancy outcomes, but most have been restricted to urban populations living near monitors. OBJECTIVES We examined the association between pregnancy outcomes and fine particulate matter in a large national study including urban and rural areas. METHODS Analyses were based(More)
The long-term impact of annual case-finding and chemotherapy with praziquantel on schistosomiasis japonica was examined in an 8-year longitudinal study in the Philippines. The prevalence, incidence, and intensity of infection and schistosome-induced hepatomegaly significantly decreased within 3-4 years of treatment and then stabilized despite continual(More)
The aim of this study was to examine spatial clustering of obesity and/or moderate physical activity and their relationship to a neighborhood's built environment. Data on levels of obesity and moderate physical activity were derived from the results of a telephone survey conducted in 2006, with 1,863 survey respondents in the study sample. This sample was(More)
The 1991 Canadian Census Cohort is the largest population-based cohort in Canada (N ¼ 2 734 835). Prior to the creation of this Cohort, no national population-based Canadian cohort was available to examine mortality by socioeconomic indicators. The 1991 Canadian Census Cohort was created via the linkage of a sub-sample of respondents from the mandatory 1991(More)
Within the group of botanical products there is a large range of variation with regard to their properties. Some products are identical to foods while others come close to or are medicines. Botanical products are regulated differently within the different member states of the European Union (EU) and globally. They are regulated either as food or as(More)
Acknowledgments There are some people that I would like to thank for their contribution to this thesis. First of all I want to express my gratitude and my appreciation to my advisor Prof. Alexander I. Bobenko, who introduced me to the field of Riemann surfaces and integrable systems, the theoretical foundations of this thesis. I am also very grateful to(More)
Partial immunity to schistosomiasis mansoni has been demonstrated in mice and has recently been transferred passively with serum, but not with cells. In vitro studies using human and rodent materials have demonstrated antibody-dependent cell-mediated damage to immature schistosomes (schistosomula); the cell involved in some of these in vitro systems appears(More)