Paul Nielsen

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In order for a program to interact with the world as well as people do, we must provide it with a great deal of commonsense about the way things work. Reasoning about the geometric interactions and motions of objects is an important part of that commonsense. Some of the most complex problems we solve involve reasoning about mechanical devices, such as(More)
The goal of Qualitative Mechanics (QNI) is to produce a common sense theory of mechanical analysis sufficient to describe the behavior of rigid body mechanisms. In order for machines to reason about manipulation of objects in the physical world we need to develop theories of mechanics sufficiently flexible to describe not only common mechanisms such as the(More)
Recent studies demonstrate diminished calcium uptake by cultured skin fibroblasts from Alzheimer patients. To determine if altered calcium homeostasis is also present in tissue taken from Alzheimer patients, calcium homeostasis was assessed in mitogen-stimulated lymphocytes. Calcium uptake by lymphocytes from Alzheimer patients was 10%-15% lower (p less(More)
The individual agents that interact in a multi-agent system typically exist along a continuum ranging from heavyweight cognitive agents (often of the " BDI " type) to lightweight agents with limited individual processing (digital ants). Most systems use agents from a single position along this spectrum. We have successfully implemented several systems in(More)
To further elucidate the molecular basis of the selective damage to various brain regions by thiamin deficiency, changes in enzymatic activities were compared to carbohydrate flux through various pathways from vulnerable (mammillary bodies and inferior colliculi) and nonvulnerable (cochlear nuclei) regions after 11 or 14 days of pyrithiamin-induced thiamin(More)
The effects of hypoxia on metabolism of 5-hydroxytryptamine (5-HT or serotonin) and 3,4-dihydroxyphenylethylamine (DA or dopamine) were compared with those on open-field activity in male CD-1 mice. Chemical hypoxia was induced with NaNO2. Hypoxia did not alter striatal concentrations of DA, 5HT, Trp, Tyr, 5-hydroxyindoleacetic acid, or homovanillic acid.(More)
This paper describes the participation of the TacAir-Soar (TAS), intelligent constructive forces in two events hosted by Air Force Research Laboratory, Mesa AZ. The first event, RoadRunner 98, was an aircrew training exercise focused on F-16 pilots and Airborne Warning and Control controllers. TAS provided " aircraft " tracks to improve the air picture and(More)