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(2011). A " laboratory of knowledge-making " for personal inquiry learning. Copyright and Moral Rights for the articles on this site are retained by the individual authors and/or other copyright owners. For more information on Open Research Online's data policy on reuse of materials please consult the policies page. Abstract— This paper describes the(More)
Copyright and Moral Rights for the articles on this site are retained by the individual authors and/or other copyright owners. For more information on Open Research Online's data policy on reuse of materials please consult the policies page. Abstract. Despite the large number and variety of tools and services available today for exploring scholarly data,(More)
Software Visualization can be defined as the use of graphical and textual formalisms to describe the execution of computer programs. A large amount of Software Visualization technology has been developed to support computer science education, using a range of interface techniques. Far less effort has been devoted to evaluating the technology. As a result,(More)
Observational studies in the literature have highlighted low levels of user satisfaction in relation to the support for ontology visualization and exploration provided by current ontology engineering tools. These issues are particularly problematic for non-expert users, who rely on effective tool support to abstract from representational details and to be(More)
Many communities exist that learn and share information either partly or wholly online. These (wholly or partially) on-line communities share messages, documents, and other artefacts that contain useful community knowledge. Members of the community learn through this sharing process, and the growing archive they create forms a valuable learning resource for(More)
For guidance on citations see FAQs. c [not recorded] Version: [not recorded] Link(s) to article on publisher's website: Copyright and Moral Rights for the articles on this site are retained by the individual authors and/or other copyright owners. For more information on Open Research Online's data policy on reuse of materials please consult the policies(More)
Isocitrate dehydrogenases (IDHs) catalyse oxidative decarboxylation of isocitrate to α-ketoglutarate (α-KG). IDH1 functions in the cytosol and peroxisomes, whereas IDH2 and IDH3 are both localized in the mitochondria. Heterozygous somatic mutations in IDH1 occur at codon 132 in 70% of grade II-III gliomas and secondary glioblastomas (GBMs), and in 5% of(More)
PURPOSE A randomized, phase III, placebo-controlled, partially blinded clinical trial (REGAL [Recent in in Glioblastoma Alone and With Lomustine]) was conducted to determine the efficacy of cediranib, an oral pan-vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor, either as monotherapy or in combination with lomustine versus(More)
Increasingly heritage institutions are making digital artifacts available to the general public and research groups to promote the active exploration of heritage and encourage visits to heritage sites. Stories, such as folklore and first person accounts form a useful and engaging heritage resource for this purpose. Story Fountain provides intelligent(More)