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Neural stem cells (NSCs) offer the potential to replace lost tissue after nervous system injury. This study investigated whether grafts of NSCs (mouse clone C17.2) could also specifically support host axonal regeneration after spinal cord injury and sought to identify mechanisms underlying such growth. In vitro, prior to grafting, C17.2 NSCs were found for(More)
Bone marrow stromal cells (MSCs) constitute a heterogeneous cell layer in the bone marrow, supporting the growth and differentiation of hematopoietic stem cells. Recently, it has been reported that MSCs harbor pluripotent stem cells capable of neural differentiation and that simple treatment of MSCs with chemical inducing agents leads to their rapid(More)
MOTIVATION Identifying the destination or localization of proteins is key to understanding their function and facilitating their purification. A number of existing computational prediction methods are based on sequence analysis. However, these methods are limited in scope, accuracy and most particularly breadth of coverage. Rather than using sequence(More)
The checkers program Chinook has won the right to play a 40-game match for the World Checkers Championship against Dr. Marion Tinsley. This was earned by placing second, after Dr. Tinsley, at the 1990 U.S. National Open, the biennial event used to determine a challenger for the Championship. This is the first time a program has earned the right to contest(More)
In 1992, the seemingly unbeatable World Checker Champion, Dr. Marion Tinsley, defended his title against the computer program Chinook. After an intense, tightly-contested match, Tinsley fought back from behind to win the match by scoring four wins to Chinook’s two, with 33 draws. This was the first time in history that a human World Champion defended his(More)
Proteome Analyst (PA) (http://www.cs.ualberta.ca/~bioinfo/PA/) is a publicly available, high-throughput, web-based system for predicting various properties of each protein in an entire proteome. Using machine-learned classifiers, PA can predict, for example, the GeneQuiz general function and Gene Ontology (GO) molecular function of a protein. In addition,(More)
In this paper we introduce a new parallel algorithm MLFPT (Multiple Local Frequent Pattern Tree) [11] for parallel mining of frequent patterns, based on FP-growth mining, that uses only two full I/O scans of the database, eliminating the need for generating the candidate items, and distributing the work fairly among processors. We have devised partitioning(More)
Parallel sorting algorithms have been proposed for a variety of multiple instruction streams, multiple data streams (MIMD) architectures. The algorithm often exploits the strengths of the machine to achieve high performance. In many cases, however, the algorithm cannot achieve comparable performance on other architectures. Parallel Sorting by Regular(More)
Neurotrophic factors exert many effects on the intact and lesioned adult central nervous system (CNS). Among these effects are prevention of neuronal death (neurotrophism) and promotion of axonal growth (neurotropism) after injury. To date, however, it has not been established whether survival and axonal growth functions of neurotrophins can be(More)
BASys (Bacterial Annotation System) is a web server that supports automated, in-depth annotation of bacterial genomic (chromosomal and plasmid) sequences. It accepts raw DNA sequence data and an optional list of gene identification information and provides extensive textual annotation and hyperlinked image output. BASys uses >30 programs to determine(More)