Paul L. Caine

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BACKGROUND Alzheimer's disease (AD) accounts for 60-80% of cases of dementia and causes significant morbidity in patients and carers, and expense for health and social services. There is a need for a validated, non-invasive and cheap test to diagnose early AD, as diagnosis may enable prompt treatment and service planning. AIM To identify emerging(More)
INTRODUCTION There is an increasing trend of self-inflicted burns noted in the literature, often seen in patients with complex psychosocial backgrounds. These patients are challenging to manage as the recovery from the acute burn may be compounded by difficult rehabilitation and suboptimal coping strategies. We aimed to review patients presenting to our(More)
INTRODUCTION Hydrotherapy is widely used in burns management however there are risks associated with its use, in particular cross-infection. Data regarding indications and techniques in common use is deficient. This study aimed to investigate hydrotherapy practices in the UK and Ireland. METHODS A survey of the hydrotherapy practice of major burn care(More)
The diagnosis of desmoplastic melanoma is challenging for both clinicians and the histopathologists. The desmoplastic melanoma often clinically presents as a non-pigmented lesion mimicking a variety of other lesions and, as result can be mistaken for a benign non-melanocytic lesion which in-turn delays diagnosis, treatment and worsens patient prognosis. In(More)
The aim of this study is to establish the nature (urgent vs. non-urgent), demographics, presentation and management of Achenbach’s syndrome and to formulate an algorithmic approach for their diagnosis and management. A systematic review and met-aggregation of literature from 1944 to 2015 in English language in MedLine, Embase and Cochrane database were(More)
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