Paul Kenneth Wright

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BACKGROUND AND PURPOSE We sought to characterize the spatial and temporal evolution of human cerebral infarction. Using a novel method of quantitatively mapping the distribution of hypoxic viable tissue identified by 18F-fluoromisonidazole (18F-FMISO) PET relative to the final infarct, we determined its evolution and spatial topography in human stroke. (More)
In ischaemic stroke, expansion of the infarct core occurs at the expense of surrounding hypoxic, metabolically compromised tissue over a period of 24 h or more in a considerable proportion of patients. It is uncertain whether hypoxic tissue observed at later times after stroke onset retains the potential for survival or whether such survival has an impact(More)
BACKGROUND AND AIMS The mismatch between perfusion weighted images (PWI) and diffusion weighted images (DWI) using MR is increasingly being applied in patient selection for therapeutic trials. Two approaches to the calculation of the mismatch volume exist--the commonly used volumetric and the more precise co-registration method, the latter of which(More)
This paper describes an algorithm for minimizing the non-productive time or 'airtime' for a tool by optimally connecting the toolpaths for that tool. This problem is formulated as a generalized traveling salesman problem with precedence constraints and is solved using a heuristic method. The performance of the heuristic algorithm and the amount of(More)
We present the architecture, implementation, and initial results from a live, continuous energy auditing system. By combining QR codes and mobile phones, we are able to iteratively collect building plug-load information and couple it with live, streaming meter data. The system consists of a deployment of inexpensive tags (QR codes) as well a(More)
In this paper we demonstrate a proof of concept that quickly linking and modifying parameters of a user based simulation driven by real device audit data is possible. Further, we demonstrate an ability to simulate basic functions and behavior of users and their appliances in an office building and have made a solid case for the continuation of this work(More)