Paul J. Litton

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We describe the epidemiology of the first nationwide outbreak of measles infection in the UK since the implementation of a mass vaccination campaign. Notifications of infectious diseases, interview and postal questionnaire identified 293 clinical cases, 138 of which were confirmed by salivary IgM, measles virus isolation and PCR. Twelve were(More)
EVIDENCE-BASED MEDICINE PRESCRIBES THAT CLINICAL practice should be guided by the results of rigorous research. The close connection between clinical research and patient care, coupled with the need for research to be conducted by physician-investigators with patients who participate in research (patient-participants), makes it difficult to appreciate how(More)