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Classic studies have recognized neurons and three glial elements in the central nervous system (CNS) - astrocytes, oligodendrocytes and microglia. The identification of novel glia that specifically express the NG2 chondroitin sulphate proteoglycan (CSPG) raises the possibility of a fifth element. Until recently, all NG2-expressing glia were considered to be(More)
— The environmental science and engineering communities are actively engaged in planning and developing the next generation of large-scale sensor-based observing systems. These systems face two significant challenges: heterogeneity of instrumentation and complexity of data stream processing. Environmental observing systems incorporate instruments across the(More)
Earthquake engineers have traditionally investigated the behavior of structures with either computational simulations or physical experiments. Recently, a new hybrid approach has been proposed that allows tests to be decomposed into independent substructures that can be located at different test facilities, tested separately, and integrated via a(More)
In the adult CNS, antibodies to the NG2 chondroitin sulphate proteoglycan (CSPG) label a large population of glia that have the antigenic phenotype of oligodendrocyte progenitor cells (OPC). However, NG2 expressing glia have the morphological phenotype of astrocytes, not OPC. We propose adult NG2 expressing glia are a distinct mature glial type, which we(More)
The NEESgrid project is revolutionizing the way earthquake engineering (EE) researchers collaborate to plan, perform, share and publish research even while being geographically separated. The proposed demonstration is in complement to the NEESgrid paper titled " Distributed Hybrid Earthquake Engineering Experiments: Experiences with a Ground-Shaking Grid(More)
BACKGROUND The development of disease-modifying therapies for Alzheimer's disease is hampered by our lack of understanding of the early pathogenic mechanisms and the lack of early biomarkers and risk factors.We have documented the expression pattern of mTOR regulated genes in the frontal cortex of Alzheimer's disease patients. We have also examined the(More)
Computational analyses of organizational behavior employ either intellective or emulative models [1]. The model described in this paper 1 is an intellective models. Intellective models are usually abstract, small, relatively simple, and incorporate only a few parameters. They help modelers make general predictions about trends and the relative benefit of(More)
As the usage of unmanned systems become more prevalent, defence departments around the world are looking for new modes of human-system interaction that increase the level of autonomy of the vehicle, while maintaining operator control and trust. Defence R&D Canada is currently engaged in a research program on the simulation of Unmanned Aerial Vehicles(More)
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