Learn More
The increasing intraneuronal accumulation of lipofuscin has been linked to the aging process by a striking linear correlation between the degree of accumulation and chronological age. It has been established that age pigments are soluble in polar and nonpolar solvents; the pigment is autofluorescent and stains with PAS, Sudan black B, Nile blue osmic acid(More)
1. The developmental time sequence of Müller cells (MC) has been described. The maturation and proliferation of MC has a far reaching effect on the architecture of the whole retina, by forming the limiting membranes, and by separating synaptic complexes of receptors and bipolars. 2. The final stage of MC maturation reveals a polar distribution of(More)
An electron microscopic study has been made of the perivascular cerebral pericytes and juxtavascular phagocytes in the human cerebral cortex. Biopsies from 16 hydrocephalic children and one 4-year-old normal child were analyzed. Pericytes showed vesicular transport demonstrating pericyte brain barrier alteration in hydrocephalus, which might help in the(More)
Four of 30 human cerebral cortex biopsies from infants ranging from four days to about ten years treated for hydrocephalus by shunt operations are described paying special attention to the vascular structures. The biopsy specimens were studied in semi-thin and ultrathin sections. Attention is drawn to the role of pinocytotic vesicles found in capillaries(More)
Three of 30 human cerebral cortex biopsies from infants treated for hydrocephalus by shunt operation are described. The descriptions include an account of their case history, the clinical methods, and the operational procedures. The biopsy specimens were studied in semithin and ultrathin sections. Attention is drawn to normal synapse formation but also to(More)
1. The cellular and synaptic pattern of the lateral geniculate body of the monkey has been studied electronmicroscopically by using microdissected portions from individual layers. For general orientation and comparison the Golgi technique has been utilised extensively. 2. This technique revealed four different types of neuron whose distribution differs in(More)