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- Gilean McVean, Philip Awadalla, Paul Fearnhead
- Genetics
- 2002

Determining the amount of recombination in the genealogical history of a sample of genes is important to both evolutionary biology and medical population genetics. However, recurrent mutation canâ€¦ (More)

- Paul Fearnhead, Peter Donnelly
- Genetics
- 2001

We introduce a new method for estimating recombination rates from population genetic data. The method uses a computationally intensive statistical procedure (importance sampling) to calculate theâ€¦ (More)

We consider the problem of detecting multiple changepoints in large data sets. Our focus is on applications where the number of changepoints will increase as we collect more data: for example inâ€¦ (More)

- Paul Fearnhead
- Statistics and Computing
- 2006

We demonstrate how to perform direct simulation from the posterior distribution of a class of multiple changepoint models where the number of changepoints is unknown. The class of models assumesâ€¦ (More)

The Kalman filter provides an effective solution to the linear-Gaussian fil tering problem. However, where there is nonlinearity, either in the model specification or the obs rvation process, otherâ€¦ (More)

- Paul Fearnhead, Zhen Liu
- 2007

We propose an on-line algorithm for exact filtering of multiple changepoint problems. This algorithm enables simulation from the true joint posterior distribution of the number and position of theâ€¦ (More)

- Meredith Yeager, Nick Orr, +32 authors Gilles Thomas
- Nature Genetics
- 2007

Recently, common variants on human chromosome 8q24 were found to be associated with prostate cancer risk. While conducting a genome-wide association study in the Cancer Genetic Markers ofâ€¦ (More)

- Paul Fearnhead
- Statistics and Computing
- 2004

We consider the analysis of data under mixture models where the number of components in the mixture is unknown. We concentrate on mixture Dirichlet process models, and in particular we consider suchâ€¦ (More)

The objective of this paper is to present a novel methodology for likelihood-based inference for discretely observed diffusions. We propose Monte Carlo methods, which build on recent advances on theâ€¦ (More)

- Daniel J. Wilson, Edith Gabriel, +7 authors Peter J Diggle
- PLoS genetics
- 2008

Campylobacter jejuni is the leading cause of bacterial gastro-enteritis in the developed world. It is thought to infect 2-3 million people a year in the US alone, at a cost to the economy in excessâ€¦ (More)