Paul Engler

Learn More
A transgene, pHRD, is highly methylated in 12 independent mouse lines when in a C57BL/6 strain background, but becomes progressively less methylated when bred into a DBA/2 background. Transgenes inherited from the mother are generally more methylated; however, this parental effect disappears following continued breeding into the nonmethylating strain.(More)
ACKNOWLEDGMENTS We are indebted to the following people for their assistance in establishing monitoring sites for the groundspray program: Disclaimer The mention of commercial products, their source or their use in connection with material reported herein is not to be construed as e either an actual or implied endorsement of such product.
The rearrangement of immunoglobulin (Ig) and T cell receptor (TCR) genes requires the activity of an as yet undefined V(D)J recombinase. One component of the recombinase appears to be a terminal transferase which may be involved in the addition of untemplated nucleotides (N regions) to the V(D)J joints. It has been observed that rearranged Ig and TCR genes(More)
  • 1