Paul E. M. Huygen

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A device to produce a stepwise indicator gas fraction variation to initiate a washout test in mechanically ventilated patients is described. The device, which can be used in conjunction with the commonly used Siemens-Elema series 900 ventilators, is based on simple, off-the-shelf technology. It features the simultaneous use of two indicator gases (so that(More)
The purpose of this study was to build an experimental set-up to assess continuously the humidification, heating and resistance properties of heat-moisture exchangers (HMEs) under clinical conditions. The experimental set-up consists of a patient model, measurement systems and a ventilator. Surgical ICU, University Hospital of Rotterdam. A clinically used(More)
A data acquisition and processing system for the analysis of inert gas wash-out tests is described. The described system is in clinical use on spontaneously breathing patients as well as on mechanically ventilated Intensive Care patients. It combines several analysis techniques with an aim to provide a deeper insight into the nature of existing ventilation(More)
OBJECTIVES a) To determine the validity of a new method to analyze indicator gas washout tests on mechanically ventilated patients. This method takes into account the difference between the end-expiratory gas fraction and the mean gas fraction in the lung and provides the end-expiratory lung volume and a new index of ventilation inhomogeneity called volumes(More)
This paper describes the experiments carried out in the context of the BEST-project, an interdisciplinary project with researchers from the Law faculty and the AI department of the VU University Amsterdam. The aim of the project is to provide laymen with information about their legal position in a liability case, based on retrieved case law. The process(More)
This paper deals with a simple tool that we have developed to support the parties in online dispute resolution (ODR). The tool helps the participants to bring forward the statements of the dispute in a structured and concise way. After each added statement the online tool shows the structured layout of the statements. As an example, the tool has been(More)
To evaluate the cardiopulmonary effects, especially the end-expiratory lung volume (EEV) and ventilation inhomogeneity during diminished early expiratory flow ventilation (DEEF), which resembles pursed-lips breathing, with the conventional intermitent positive pressure ventilation (IPPV) in postoperative mechanically ventilated patients with chronic(More)
Objective: To evaluate a simple device which injects a constant fraction of indicator gas to the inspiratory mixture for performing multi-breath wash-out tests during controlled ventilation.Design: the technique in which the indicator gas is injected at the mouth of the patient (post-mix) is compared with the technique where the indicator gas is(More)
DEEP is a ventilation mode where the expiratory flow is limited and can be compared with pursed lips expiration during spontaneous breathing. The flow limitation is expected to prevent airway collapse and improve gas exchange in flaccid lungs. We compared DEEF with the conventional IPPV mode and to eliminate the effect of airway pressures, a small amount of(More)