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  • Karine Brudey, Jeffrey R. Driscoll, +63 authors Christophe Sola
  • Biology, Medicine
  • BMC Microbiology
  • 2005 (First Publication: 6 March 2006)
  • BackgroundThe Direct Repeat locus of the Mycobacterium tuberculosis complex (MTC) is a member of the CRISPR (Clustered regularly interspaced short palindromic repeats) sequences family. SpoligotypingContinue Reading
  • Nicolaas Claudius Gey van Pittius, Samantha Leigh Sampson, Hyeyoung Lee, Yeun Kim, Paul D van Helden, Robin Mark Warren
  • Biology, Medicine
  • BMC Evolutionary Biology
  • 2006 (First Publication: 15 November 2006)
  • BackgroundThe PE and PPE multigene families of Mycobacterium tuberculosis comprise about 10% of the coding potential of the genome. The function of the proteins encoded by these large gene familiesContinue Reading
  • Madeleine Hanekom, Gian D. van der Spuy, +7 authors Robin Mark Warren
  • Biology, Medicine
  • Journal of clinical microbiology
  • 2007 (First Publication: 1 May 2007)
  • This study aimed to reconstruct the evolutionary history of Beijing strains of Mycobacterium tuberculosis and to test the hypothesis that evolution has influenced the ability of the Beijing strainsContinue Reading
  • Robin Mark Warren, Thomas Calldo Victor, +4 authors Paul D van Helden
  • Medicine
  • American journal of respiratory and critical care…
  • 2004 (First Publication: 1 March 2004)
  • It is generally accepted that tuberculosis results from a single infection with a single Mycobacterium tuberculosis strain. Such infections are thought to confer protective immunity against exogenousContinue Reading
  • Suzanne Verver, Robin Mark Warren, +6 authors Paul D van Helden
  • Medicine
  • American journal of respiratory and critical care…
  • 2005 (First Publication: 15 June 2005)
  • RATIONALE In a high-tuberculosis (TB) incidence area of Cape Town, South Africa, there is a very high rate of unexplained recurrent TB. The incidence of new bacteriologically confirmed disease in theContinue Reading
  • Keertan Dheda, Tawanda Gumbo, +39 authors Robin Mark Warren
  • Medicine
  • The Lancet. Respiratory medicine
  • 2017 (First Publication: 1 April 2017)
  • Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis remains out of control in several parts of the world including Africa and Asia. Although tuberculosisContinue Reading