Paul Craig

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Microarrays are a relatively new, high-throughput data acquisition technology for investigating biological phenomena at the micro-level. One of the more common procedures for microarray experimentation is that of the microarray time-course experiment. The product of microarray time-course experiments is time-series data, which subject to proper analysis has(More)
Microarrays technologies are a relatively new development that allow biologists to monitor the activity of thousands of genes (normally around 8,000) in parallel across multiple stages of a biological process. While this new perspective on biological functioning is recognised as having the potential to have a significant impact on the diagnosis, treatment,(More)
Current techniques for visualising large-scale microarray data are unable to present temporal features without reducing the number of elements being displayed. This paper introduces a technique that overcomes this problem by combining a novel display technique, which operates over a continuous temporal subset of the time series, with direct manipulation of(More)
The accumulation of protein structural data occurs more rapidly than it can be characterized by traditional laboratory means. This has motivated widespread efforts to predict enzyme function computationally. The most useful/accurate strategies employed to date are based on the detection of motifs in novel structures that correspond to a specific function.(More)
This paper presents work to support collaborative visualisation and data analysis in the microarray time-series explorer (MaTSE) software. We introduce a novel visualisation component called the 'pattern browser' which is used to support the annotation and adjustment of user queries. This includes an explanation of why this component is required and how it(More)
Cognitonics is a new science which looks at ways to reconcile human socio-spiritual development with increasingly rapid human intellectual development in the new context of technological advances and increased cultural homogeny. This is particularly relevant in areas such as education and informatics where children are found to be increasingly capable to(More)