Paul Cole

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Poly(ADP-ribose)polymerase-1 (PARP-1) is a highly abundant chromatin-associated enzyme present in all higher eukaryotic cell nuclei, where it plays key roles in the maintenance of genomic integrity, chromatin remodeling and transcriptional control. It binds to DNA single- and double-strand breaks through an N-terminal region containing two zinc fingers, F1(More)
This panel will present initial findings on the design, pilot implementation and research of TeamRoom, an innovative Louts Notes application. The application was designed initially to support temporary task teams and was extended to support ongoing , distributed and co-located work and management teams. TeamRoom represents early exploration into the(More)
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