Paul C. Wilson

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It is often difficult to assess small bowel recovery in adults with coeliac disease on a gluten-free diet (GFD). This prospective study compares changes in intestinal permeability with changes in intestinal biopsy at various intervals after commencing a GFD. Intestinal permeability was measured by lactulose/rhamnose absorption from 1 week to 24 months after(More)
Intestinal pseudo-obstruction is a rare paraneoplastic manifestation of small-cell carcinoma of the lung. This report documents a further case associated with neuronal degeneration of enteric neural plexuses and a high serum titre of immunoglobulin G (IgG) type 1 anti-neuronal nuclear antibodies (ANNA-1).
(2008) Probabilistic classification of acute myocardial infarction from multiple cardiac markers, Pattern Analysis & Applications. (Appeared in the Online First service prior to inclusion in a specific voume). Abstract Logistic regression and Gaussian mixture model (GMM) classifiers have been trained to estimate the probability of acute myocardial(More)
Surface topographical detail in human buccal smears of normal and irradiated tissue have been studied with scanning electron microscopy. Cells collected by buccal smearing show patterns of microplicae and microvilli, although such detail is occasionally masked by mucus and to a lesser extent by debris and bacteria. Buccal smearing permits collection of(More)
A new method of examining the scrotum by ultrasound with an automated water-path scanner is described. This method allows immobility of the scrotum in a more acceptable and painless way than in contact scanning methods. Panoramic scans of the entire scrotum and precision tomographic plane placement are advantages over conventional techniques. A description(More)
Misoprostol, a prostaglandin E1 analogue was administered orally to male volunteers in doses of 50, 100, 200 and 400 mcg and its effects on gastric secretion compared with those observed following placebo. All doses significantly inhibited basal acid secretion by up to 98% and also inhibited histamine-stimulated secretion during the first 60 minutes of(More)
BACKGROUND The purpose of this study was to assess the structure and function of the small intestine before and after enteral feeding given via a percutaneous feeding gastrostomy (PEG). It is not known whether this method of feeding provides a good luminal drive to the small intestine. METHODS Studies were performed of patients at the time of PEG(More)