Paul Bogowicz

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Clinical trials employ sequential analysis for the ethical and economic benefits it brings. In dentistry, as in other fields, resources are scarce and efforts are made to ensure that patients are treated ethically. The objective of this systematic review was to characterise the use of sequential analysis for clinical trials in dentistry. We searched various(More)
Assessments of skeletal maturation (ASM) are used by clinicians to optimize treatments for each patient. This study examines the interrelationship between and limitations of hand-wrist and cervical vertebrae maturation methods in adolescent patients. Radiographs (hand-wrist and lateral cephalometric) were obtained from patients (n=62, 11 to 17 years of age)(More)
This paper considers the sequential monitoring of multi-armed longitudinal clinical trials. We describe an approach that is relatively simple and accessible. Sequential ranks are used to form partial sum statistics, yielding processes that have independent increments, and hence can be approximated by Brownian motions. Three monitoring procedures are(More)
OBJECTIVES Evaluate the effect of bone-anchored maxillary expander (BAME) treatment on palatal cortical bone in adolescent patients. STUDY DESIGN Forty-two patients were assigned to two groups: treatment and control. CBCT scans were obtained for patients at baseline and 12 months later. Landmarks were placed between the second maxillary premolar and first(More)
OBJECTIVE To assess growth of the middle/posterior cranial base during adolescence based on landmarks located on serial three-dimensional cone-beam computerized tomography (CBCT) images. MATERIALS AND METHODS CBCT scans from 62 adolescents (11 to 17 years) at baseline and 12 months were used. Eleven landmarks in the cranial base were identified. Linear(More)
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