Paul Arthur Greenberg

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An electrode drive is described for recordings of neurons in freely moving and chaired monkeys during the performance of behavioural tasks. The electrode drives are implanted for periods of up to 6 months, and can advance up to 42 electrodes using 14 independent drive mechanisms. The drive samples 288 points within a 12 mmx12 mm region, with 15 mm of(More)
BACKGROUND Parkinson's disease (PD) disrupts temporal processing, but the neuronal sources of deficits and their response to dopamine (DA) therapy are not understood. Though the striatum and DA transmission are thought to be essential for timekeeping, potential working memory (WM) and executive problems could also disrupt timing. METHODOLOGY/FINDINGS The(More)
Stable multiday recordings from the dorsolateral prefrontal cortex of 2 monkeys performing 2 Go/NoGo visual-discrimination tasks (one requiring well-learned responses, the other requiring learning) demonstrate that the majority of prefrontal neurons were "functionally stable". Recordings were made using a series of removable microdrives, each implanted for(More)
“Stable multi-day recordings from chronically implanted microelectrodes within the dorsolateral prefrontal cortex of two monkeys performing three Go/NoGo visual discrimination tasks (one requiring well-learned responses, two requiring learning) demonstrated that the majority of prefrontal neurons were ‘functionally stable’. Action potentials of 94 neurons(More)
Four methods were tried in order to reduce the growth of granulation tissue on the dura. The best results were obtained using white petrolatum jelly, which almost completely suppressed the growth of granulation tissue when the recording chamber was filled with petrolatum. Collagen and acrylic seals were very effective in one monkey. Panalog ointment slowed(More)
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