Paul Aiken

  • Citations Per Year
Learn More
Multidrug resistance in human renal cell carcinoma is mainly caused by expression of the MDR1 gene and is characterized by a broad spectrum cross resistance to many natural product chemotherapeutic agents. This resistance can be overcome by applying chemosensitizers which inhibit the function of the MDR1 gene product P-glycoprotein. The development of new(More)
G, = noise generator k = integral value of B/T K , = controller gain K , = process gain n, = noise sequence s = Laplace transform variable s, = coefficients of the polynomial 6(B) (denominator of G,(B)) t = time T = sampling interval X,(B) = transfer function of forward loop controller (Table 111) y = system output ut = controller signal a = relative(More)
  • 1