Paul A. Sheahan

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A diverse collection of tetracycline derivatives has been synthesized utilizing Heck, Suzuki, and other palladium-coupling reactions via tetracycline arenediazonium and iodoarene salts. Large numbers of tetracyclines are now possible via these reactions, including numerous upper periphery derivatives of doxycycline, minocycline, sancycline, and methacycline(More)
In response to the growing water crisis in Australia, the Bureau of Meteorology has been given a mandate to develop and maintain an integrated national water information system. Section 126 of the Commonwealth Water Act 2007 provides for the making of Regulations to support these functions, which came into effect on 30th June 2008. These regulations (BoM,(More)
However, controlled vocabularies have other important roles in distributed systems: in particular in constraining content validity. A national water information system established by the Australian Bureau of Meteorology (’the Bureau’) has deployed a system for ingestion of data from multiple providers. This uses a HTTP interface onto separately maintained(More)
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