Patrizia Ferrari

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BACKGROUND The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K+-ATPase and mutated adducin. Rostafuroxin lowered blood pressure (BP) in some animal models and in(More)
α-and β-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy Abstract Adducins are cytoskeletal actin-binding proteins (α, β, γ) that function as heterodimers and heterotetramers and are encoded by distinct genes. Experimental and clinical evidence implicates α-and β-adducin(More)
Molti strumenti, basati su diverse tecnologie, sono in uso da alcuni anni per misurare la funzionalità piastrinica ex vivo. L’aggregometria a impedenza (multiple electrode aggregometry, MEA) è uno di questi sistemi di monitoraggio: l’aggregazione piastrinica nel sangue intero viene misurata dalle modifiche di impedenza elettrica causate dall’adesione delle(More)
volume and composition. It is published 12 times a year (monthly) by the American Physiological Society, 9650 relating to the kidney, urinary tract, and their respective cells and vasculature, as well as to the control of body fluid publishes original manuscripts on a broad range of subjects
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