Patrick Williams

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BACKGROUND The CCL2 chemokine is involved in promoting cancer angiogenesis, proliferation and metastasis by malignancies that express CCR2 receptor. Thus the CCL2/CCR2 axis is an attractive molecular target for anticancer drug development. METHODS We have generated a novel fusion protein using GMCSF and an N-terminal truncated version of MCP1/CCL2 (6-76)(More)
In recent years, increasing evidence indicating numerous health benefits associated with the intake of probiotic bacteria has created a big market of probiotic foods worldwide. However, maintaining high numbers of viable cells in probiotic food products during the shelf life of the product and during gastrointestinal transit is a challenge. The goal of this(More)
This article describes and interprets the results of interviews with 21 pioneering organization development (OD) thought leaders regarding the past, present, and future of the field. Interpretations of the data reveal a pattern of responses that reflects the evolution of the field; adds to our understanding of the definition, values, skills, and trends in(More)
In this study we sought to explore how experience with specific mental and somatic practices is associated with wisdom, using self-report measures of experience and wisdom. We administered standard surveys to measure wisdom and experience among four groups of practitioners of mental and somatic practices, namely, meditators, practitioners of the Alexander(More)
Objective: We appraised the differences and similarities in awareness, attitude, beliefs, misconceptions and the various high-risk behaviors that influence the rate of infectiousness of HIV/AIDS among African American (AA) women in two unequal US inner-city communities of Baltimore, Maryland and Dover, Delaware. Methods: A cross-sectional convenience-sample(More)
This issue of the McGill Journal of Medicine marks something of an anniversary for the Journal, and before commenting on the articles in this issue, we thought this a fitting time for reflection on the state of the MJM. Though we chart our recent history through a period of beginning, ending, and beginning and ending again, we have embarked with conviction(More)
EDITORIAL From the Editor's Desk: The emergence of "personalized medicine" in medical care Medical students throughout their education are taught to consider the patient as a whole. We are reminded through our course work and by our course instructors that understanding the pathophysiologic basis of disease and responding with clinical interventions are(More)
Mission: The Permanente Journal is written and published by the clinicians of the Permanente Medical Groups and KFHP to promote the delivery of superior health care through the principles and benefits of Permanente Medicine.
  • Richard Abrohams, Terry Bream, Brian Budenholzer, Dan Cherkin, Linda Fahey, Tom Godfrey +430 others
  • 2006
Mission: The Permanente Journal is written and published by the clinicians of the Permanente Medical Groups and KFHP to promote the delivery of superior health care through the principles and benefits of Permanente Medicine.