Patrick Wainwright

Learn More
Prior research had indicated that moderate maternal ethanol consumption during gestation affected the growth of the corpus callosum and anterior commissure in BALB/c mice when measured at day 19 postconception. Our purpose was to assess whether or not this was an enduring effect. Pregnant BALB/cCRBL mice were fed ethanol 10% v/v in the drinking water from(More)
The development of the corpus callosum (CC) was examined in BALB/cCF mice in relation to the effects of a 32-h period of maternal fasting. The treatment was imposed on days 15 and 16 during gestation, which immediately precedes the time when the initial callosal axons cross the midline. The BALB/c strain was used because it is prone to developing a corpus(More)
Series of fetuses from two inbred mouse strains, BALB/cCF and C57BL/6J, were collected at the time during which the corpus callosum (CC) crosses midline. Fetuses from each strain were matched initially with respect to chronological age, then morphological age and finally brain weight, and in each case the CC was assessed for presence at midline. The results(More)
A few months ago, the Brazilian Society for Neuroscience and Behavior (SBNeC) promoted a "virtual symposium" (by Internet, under the coordination of R.C.A. Guedes) on "Nutrition and Brain Function". The discussions generated during that symposium originated the present text, which analyzes current topics on the theme, based on the multidisciplinary(More)
The development of two forebrain fiber tracts, the anterior commissure (CA) and corpus callosum (CC), was examined in BALB/cCF laboratory mice in relation to the maternal dietary protein concentration during gestation. The diets contained either 8 or 27% casein. The BALB/c strain was used because it is prone to having a corpus callosum which is either(More)
Non-alcoholic fatty liver disease (NAFLD) represents a wide spectrum of liver disease from simple steatosis, to steatohepatitis, (both with and without liver fibrosis), cirrhosis and end-stage liver failure. NAFLD also increases the risk of hepatocellular carcinoma (HCC) and both HCC and end stage liver disease may markedly increase risk of liver-related(More)
Non‐alcoholic fatty liver disease (NAFLD) represents a wide spectrum of liver disease 12 from simple steatosis, to steatohepatitis, (both with and without liver fibrosis), cirrhosis and 13 end‐stage liver failure. NAFLD also increases the risk of hepatocellular carcinoma (HCC) and both 14 HCC and end stage liver disease may markedly increase risk of(More)
The development of two forebrain fiber tracts, the corpus callosum and anterior commissure was examined in BALB/cCF and C57BL/6J mice in relation to moderate maternal consumption of ethanol during gestation. Pregnant animals were fed ethanol 10% v/v in the drinking water from days 5 to 19 of gestation, when fetal brain development was assessed. Control(More)
  • 1