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Administration 2012a) states that replacement rates for the medium earner rose from about 30 percent in the 1970s to 40 percent in the 1980s, where they remain today. But replacement rates for individuals and households depend on more than Social Security provisions. They also depend on labor force activity and household arrangements. While an extensive(More)
for helpful discussions and comments. All opinions and any mistakes are the authors' and should not be attributed to the staff, officers or trustees of any of the institutions with which they are affiliated. ABSTRACT A variety of recent studies have found that the United States faces a substantial fiscal gap — that is, a sizable imbalance between projected(More)
We describe 2 patients with Parkinson's disease who developed hepatotoxicity associated with the use of entacapone, a novel, mainly peripheral acting inhibitor of catechol-D-methyltransferase. Hepatotoxicity resolved rapidly with discontinuation of the drug. Analysis of causality in a further case initially linked to entacapone exposure was confounded by(More)
OBJECTIVES To identify risk factors predisposing to the development of flucloxacillin associated jaundice. DESIGN Case-control study. Medical records of cases and controls were reviewed and information recorded on standard data collection forms. SETTING Alfred Hospital recruiting subjects from Melbourne, Sydney, and Brisbane. SUBJECTS Cases were(More)
OBJECTIVES To identify risk factors for the development of amoxycillin-clavulanic acid associated jaundice. DESIGN Retrospective case-control study. Cases were selected from those reported to the Adverse Drug Reactions Advisory Committee from the time of introduction of amoxycillin-clavulanic acid to Australia in 1986 until December 1993. SUBJECTS(More)
National voluntary reporting systems generate large volumes of clinical data pertinent to drug safety. Currently descriptive statistical techniques are used to assist in the detection of drug safety 'signals'. Australian data have been coded according to guidelines formulated almost 30 years ago and which have resulted in many drugs which are not associated(More)
The Adverse Drug Reactions Advisory Committee (ADRAC) database collates notifications of adverse events following immunisation (AEFI) from across Australia. The data were analysed for vaccines received between 1 January 2000 and 30 September 2002. Dose-based AEFI reporting rates were calculated using denominator data from the Australian Childhood(More)
The man-computer interface has evolved from the tele-typewriter to workstations that accomplish a spatial metaphor for data management. In the experimental system described here, speech and graphics techniques are used to produce an interface in the form of a metaphorical person. Interaction takes the form of an unconstrained spoken conversation with a(More)