Patrick Poullet

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MOTIVATION Genome-wide functional annotation either by manual or automatic means has raised considerable concerns regarding the accuracy of assignments and the reproducibility of methodologies. In addition, a performance evaluation of automated systems that attempt to tackle sequence analyses rapidly and reproducibly is generally missing. In order to(More)
Precision medicine (PM) requires the delivery of individually adapted medical care based on the genetic characteristics of each patient and his/her tumor. The last decade witnessed the development of high-throughput technologies such as microarrays and next-generation sequencing which paved the way to PM in the field of oncology. While the cost of these(More)
  • Christian R H Raett, William Dowhan, Nan Wang, Kun Yan, Mark M Rasenick, Harry B Smith +313 others
  • 2001
MINIREVIEW Biosynthesis and function of phospholipids in Esch-erichia coli. COMMUNICATIONS Tubulin binds specifically to the signal-transducing proteins, G, and Gi.1. An engineered change in substrate specificity of ribulosebisphosphate carboxylase/oxygenase. Stimulation of glycine catabolism in isolated per-fused rat liver by calcium mobilizing hormones(More)
We have previously shown that the detection of gene fusion events can contribute towards the elucidation of functional associations of proteins within entire genomes. Here we have analysed the entire genome of Drosophila melanogaster using fusion analysis and two additional constraints that improve the reliability of the predictions, viz. low sequence(More)
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