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The number of cores integrated onto a single die is expected to climb steadily in the foreseeable future. This move to many-core chips is driven by a need to optimize performance per watt. How best to connect these cores and how to program the resulting many-core processor, however, is an open research question. Designs vary from GPUs to cache-coherent(More)
  • Gaia Nebbia, Dimitra Peppa, Anna Schurich, Pooja Khanna, Harsimran D. Singh, Yang Cheng +6 others
  • 2012
The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and induces their apoptotic deletion or functional inactivation. We investigated whether galectin-9/Tim-3 interactions contribute to the deletion and exhaustion of the antiviral T cell response in chronic hepatitis B virus infection (CHB). We found Tim-3 to be expressed(More)
OBJECTIVE In this report, we present a rare case of avascular necrosis (AVN) in an otherwise healthy 42-year-old male patient treated with low dose oral corticosteroids for his bronchitis. A systematic review of the literature related to AVN and corticosteroids was performed. CASE REPORT Forty-two-year-old male with no underlying conditions predisposing(More)
  • Kerstin A. Stegmann, Francis Robertson, Navjyot Hansi, Upkar Gill, Celeste Pallant, Theodoros Christophides +8 others
  • 2016
Natural killer cells (NK) are highly enriched in the human liver, where they can regulate immunity and immunopathology. We probed them for a liver-resident subset, distinct from conventional bone-marrow-derived NK. CXCR6+ NK were strikingly enriched in healthy and diseased liver compared to blood (p < 0.0001). Human hepatic CXCR6+ NK had an immature(More)
The feeling of being in the zone (related to "flow") is marked by an elevated yet effortless sense of concentration. Prior research suggests that feelings of being in the zone are strongest when the demand posed by a task matches one's level of ability (i.e., the balance hypothesis). In the present article, we tested this hypothesis using a novel(More)
The trophoblast cells are in direct contact with endometrial tissues throughout gestation, playing important early roles in implantation and placentation. The physiologic significance and the operating mechanisms involved in probable altered trophoblast functions following Chlamydia trachomatis infection were investigated to determine if C. trachomatis(More)
T he Community Collaborative Rain, Hail, and Snow Network (CoCoRaHS) originated in the aft ermath of a fl ash-fl ood storm that dropped more than 12-in. of rain over a small portion of Fort Collins, Colorado, on 28 July 1997, and a similar storm the following evening over the grasslands of northeastern Colorado. Th ese fl oods were responsible for several(More)
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