Patrick Keller

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Major multi-user systems based on VRML are mainly used to set up virtual communities on the Web. The ability of these systems to take in account the reality as an input or output is non-existent. They are restricted to the Web. We propose a more generic architecture that permits to set up 3D shared environments (by using VRML or not) but also to interact(More)
The detection and quantification of methylated RNA can be beneficial to understand certain cellular regulation processes such as transcriptional modulation of gene expression, immune response, or epigenetic alterations. Therefore, it is necessary to have methods available, which are extremely sensitive and accurate, for instance liquid chromatography-tandem(More)
The project offers two distinct parts. First, there is an online architectural project devoted to the museum and the new technological, mobile, "downloadable," "virtual," and digital spaces. It is mainly concerned with developing a prototype of a "virtual museum" or a "realvirtual museum," hybrid located in several territories and true extension of the(More)
Microbial nucleic acids have been described as important activators of human innate immune responses by triggering so-called pattern recognition receptors (PRRs) that are expressed on innate immune cells, including plasmacytoid dendritic cells and monocytes. Although host and microbial nucleic acids share pronounced chemical and structural similarities,(More)
The combination of the field of architecture and currently available multi-user technology could be considered as an ideal testbed for designing the vision of shared cyberspaces. A concrete CAAD course is described to demonstrate how architectural knowledge is used to create a virtual exhibition inside an online, three-dimensional, avatar-based environment.(More)
Nucleoside methylations and other nucleic acid modifications have recently encountered a surge in interest, prompted, among other things, by the detection of methylation and active demethylation of DNA and mRNA by similar mechanisms. In DNA, deoxycytidine methylation by Dnmt enzymes generates 5-methyldeoxycytidine, an important epigenetic mark that(More)
Introduction _knowscape mobile is an architectural space associating territories of data and physical space, linking architecture, knowledge and browsing. Initially _knowscape has been conceived as an alternative multi-user browser using data *tracking* and *profiling* techniques to question, to reverse them, so to finally produce open data territories,(More)
Major multi-user systems based on VRML are mainly used to set up virtual communities on the Web. The ability of these systems to take in account the reality as an input or output is non-existent. They are restricted to the Web. We propose a more generic architecture that permits to set up 3D shared environments (by using VRML or not) but also to interact(More)
Developmental research in music has typically centered on the study of single musical skills (e.g., singing, listening) and has been conducted with middle class children who learn music in schools and conservatories. Information on the musical development of children from different social strata, who are enrolled in community-based music programs, remains(More)