Patrick K Whalen

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OBJECTIVE To measure predefined clinical effects resulting from the use of epidural anesthesia and analgesia during and after cardiac surgery. DESIGN Prospective, randomized, nonblinded clinical trial. SETTING Single academic medical center. PARTICIPANTS Sixty patients scheduled for elective cardiac surgery with cardiopulmonary bypass. INTERVENTIONS(More)
Pathological laughing and crying is a disorder of emotional expression seen in a number of neurological diseases. The aetiology is poorly understood, but clinical descriptions suggest a disorder of emotion regulation. The goals of this study were: (i) to characterize the subjective, behavioural and physiological emotional reactions that occur during(More)
Although previous research suggests that overall emotional reactivity does not change with normal aging, it is possible that different emotions follow different developmental courses. We examined emotional reactivity to films selected to elicit sadness, disgust, and a neutral state in young, middle-aged and older adults (total N = 222). Physiology and(More)
UNLABELLED Diabetic patients are at increased risk of wound infection after major surgery, but the effect of perioperative glucose control on postoperative wound infection rates after surgery is uncertain. We tested the effect of an insulin infusion on perioperative neutrophil function in diabetic patients scheduled for coronary artery bypass surgery.(More)
OBJECTIVE To measure the effects of glucocorticoids on the systemic inflammatory response and clinical recovery after cardiac surgery. DESIGN Randomized, prospective, double-blind, placebo-controlled clinical trial with concurrent comparison groups. SETTING University medical center. PARTICIPANTS Patients scheduled for elective coronary artery bypass(More)
UNLABELLED The purpose of this questionnaire survey was to provide an overview of anesthesiology pain fellowship programs in the United States with regard to implantation of spinal cord stimulators (SCS) and opioid infusion devices. Of the 95 programs solicited, 80% responded to questions pertaining to the prevalence of use and technical considerations of(More)
The present research examined the effect of the 5-HTTLPR polymorphism in the serotonin transporter gene on objectively coded positive emotional expressions (i.e., laughing and smiling behavior objectively coded using the Facial Action Coding System). Three studies with independent samples of participants were conducted. Study 1 examined young adults(More)
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