Patrick K. Notz

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The behavioural and biochemical effects of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists, dizocilpine and memantine, and the competitive NMDA receptor antagonist, CGP 39551, were investigated in rats. Systemic injections of dizocilpine (0.33 mg/kg) increased locomotion and rearing in an open field, whereas memantine (20 mg/kg)(More)
Multiphysics simulation software is plagued by complexity stemming from nonlinearly coupled systems of Partial Differential Equations (PDEs). Such software typically supports many models, which may require different transport equations, constitutive laws, and equations of state. Strong coupling and a multiplicity of models leads to complex algorithms (i.e.,(More)
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