Patrick John Rice

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Cognitive processing inefficiency, often measured using digit symbol coding tasks, is a putative vulnerability marker for schizophrenia and a reliable indicator of illness severity and functional outcome. Indeed, performance on the digit symbol coding task may be the most severe neuropsychological deficit patients with schizophrenia display at the group(More)
Vibration perception threshold (VPT) is increasingly used as a measure of large nerve fibre function in studies of patients with diabetes and in other disorders. In order to establish the influence of age, height, sex, and smoking on VPT values in the normal population and to allow the calculation of accurate age-related percentile charts, 1365 healthy(More)
Pathological studies of a sural nerve biopsy in a man with Tangier disease presenting as a remitting-relapsing multifocal neuropathy showed abnormalities in the paranodal regions, including lipid deposition (65%) and redundant myelin foldings, with various degrees of myelin splitting and vesiculation (43%) forming small tomacula and abnormal myelin terminal(More)
The activity of the enzyme tyrosine hydroxylase (TH) can be increased in the rat superior cervical ganglion by stimulating the preganglionic cervical sympathetic trunk. Since nicotinic, muscarinic and alpha adrenergic receptors have been implicated in ganglionic transmission, the role of each of these receptors in the trans-synaptic regulation of TH(More)
1. Unilateral denervation of the rat vas deferens (RVD) was performed under anesthesia. The animals were allowed to recover 4 or 10 days and then concentration-effect (C-E) curves to noradrenaline (NA) and neurokinin A (NKA) were constructed in denervated and control RVD. 2. Tissues denervated 4 or 10 days produced NA responses shifted 20-fold to the left(More)
The goal of the current study is the development of a long lasting shark repellent bait to reduce elasmobranch bycatch during commercial pelagic longline (PLL) fishing. Currently, twelve preliminary at-sea trials have been completed, which have identified a candidate long lasting and effective shark repellent bait for further experimental at-sea(More)
(2004) " Invertebrate LocOlympics: An investigation and inquiry into invertebrate locomotion and biomechanics, " In: Tested Studies for Laboratory Teaching ((2001) Lethal and sublethal effects of ivermectin in a freshwater oligochaete, Lumbriculus variegatus. Drewes, C. (1999) " Non-invasive recording of giant nerve fiber action potentials from freely(More)
Secretin and VIP stimulate cardiac adenylyl cyclase activity and exert a positive inotropic action in several mammalian species. This study examined positive inotropic activity and cAMP levels in rat papillary muscle. Isoproterenol and secretin increased contractions by 150+/-31% and 129+/-27%, respectively. VIP increased contraction by 30+/-21% only at 10(More)