Patrick J. Rogler

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Cannabinoid receptors 1 and 2 (CB1 and CB2, respectively) are part of the endocannabinoid system along with intracellular enzymes (such as fatty acid amide hydrolase, FAAH) that degrade endocannabinoid ligands. Exogenous cannabinoids are potential therapeutics for treating neurological sequalae in HIV-infected patients because cannabinoids can suppress the(More)
A series of ferrous-heme 2,6-dimethylphenyl isocyanide (DIMPI) and ferrous-heme mononitrosyl complexes have been synthesized and characterized. The heme portion of the complexes studied is varied with respect to the nature of the axial ligand, including complexes, where it is covalently tethered to the porphyrinate periphery. Reduced heme complexes,(More)
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