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The strength of synaptic communication at central synapses depends on the number of ionotropic glutamate receptors, particularly the class gated by the agonist AMPA (AMPARs). Cornichon proteins, evolutionarily conserved endoplasmic reticulum cargo adaptors, modify the properties of vertebrate AMPARs when coexpressed in heterologous cells. However, the(More)
According to the PubMed resource from the U.S. National Library of Medicine, over 750,000 scientific articles have been published in the ~5000 biomedical journals worldwide in the year 2007 alone. The vast majority of these publications include results from hypothesis-driven experimentation in overlapping biomedical research domains. Unfortunately, the(More)
To date, our understanding of a normal immune system is far behind that of other healthy organ systems. One reason for this is the lack of standardization in the lab techniques, especially flow cytometry. To take a step towards the characterization of a normal immune system, we re-analyzed and combined data that was made publicly available through the(More)
INTRODUCTION In the present study, we sought to identify markers in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) that distinguish those achieving remission at 6 months following rituximab or cyclophosphamide treatment from those for whom treatment failed in the Rituximab in ANCA-Associated Vasculitis (RAVE) trial. (More)
  • Amanda G Stanley, Thomas N Kaye, Peter W Dunwiddie, Stephanie Miller, Jon Bakker, Andrew Macdougall +44 others
  • 2010
A cooperative project jointly funded by PREFACE This report is the result of a cooperative project between the Institute for Applied Ecology (IAE) and The Nature Conservancy (TNC). IAE is a non-profit organization dedicated to natural resource conservation, restoration, research, and education. Our mission is to conserve native species and habitats through(More)
M obile telecommunication technologies have spurred growth and innovation in multiple sectors including commerce, media, and finance. Arguably, health care is the sector in which the potential of these new technologies is both the greatest and the most unrecognized. With the rapid adoption of electronic health records (EHRs) and patient access to mobile(More)
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