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  • Yu Liang, Suizhen Lin, +10 authors Steven M Paul
  • Medicine, Biology
  • Journal of neurochemistry
  • 2004 (First Publication: 1 February 2004)
  • Apolipoprotein E (apoE) is an important protein involved in lipoprotein clearance and cholesterol redistribution. ApoE is abundantly expressed in astrocytes in the brain and is closely linked to theExpand
  • Xian-cheng Jiang, Thomas P. Beyer, +7 authors Guoqing Cao
  • Chemistry, Medicine
  • Journal of Biological Chemistry
  • 2003 (First Publication: 5 December 2003)
  • The factors involved in the generation of larger high density lipoprotein (HDL) particles, HDL1 and HDLc, are still not well understood. Administration of a specific synthetic liver X receptor (LXR)Expand
  • Yue-wei Qian, Robert J. Schmidt, +14 authors Guoqing Cao
  • Medicine, Biology
  • Journal of Lipid Research
  • 2007 (First Publication: 1 July 2007)
  • Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protease that regulates low density lipoprotein receptor (LDLR) protein levels. The mechanisms of this action, however, remain to beExpand
  • Heather Fraser, Colin Hislop, +6 authors Joaquim Trias
  • Medicine
  • Journal of cardiovascular pharmacology
  • 2009 (First Publication: 1 January 2009)
  • The family of secretory phospholipase A2 (sPLA2) enzymes has been associated with inflammatory diseases and tissue injury including atherosclerosis. A-001 is a novel inhibitor of sPLA2 enzymesExpand
  • Jeffrey Thomas, Kelli S. Bramlett, +11 authors Laura F. Michael
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2003 (First Publication: 24 January 2003)
  • Fenofibrate is clinically successful in treating hypertriglyceridemia and mixed hyperlipidemia presumably through peroxisome proliferator-activated receptor α (PPARα)-dependent induction of genesExpand