Patrick H. Lehan

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&HEEL, KONRAD Mr., MANUEL BANET, COBERN OTT, AND PATRICK H. LEHAN. A quantitative approach to collateral and antegrade flows after coronary occlusion. Am. J. Physiol. 222(3): 687-694. 1972.-In an isolated dog heart preparation, the circumflex, anterior descending, and right coronary arteries were simultaneously perfused and blood flow was monitored by(More)
Thirty-two thousand patients are presently maintained in chronic dialysis programs. Cardiovascular complications have been shown to be responsible for 50 to 65% of the deaths in such patients. Despite this and the increasingly frequent use of coronary bypsss surgery in the general population, only two patients have previously been reported to have(More)
The hemodynamic, electrocardiographic, and metabolic responses of dogs with acute myocardial ischemia to intravenous administration of fructose-1,6-diphosphate (FDP) were assessed. Analysis of the results (compared to dextrose control) revealed evidence of major improvement of LVEDP and cardiac output, significant decrease of the ST segment, and large(More)
We compared the short-term hemodynamic effects of intravenous fructose 1,6-diphosphate (FDP) administration in patients with coronary artery disease. Hemodynamic measurements were performed before and after administration of FDP in two groups of patients: those with impaired left ventricular (LV) function, elevated LV end-diastolic pressures (LVEDP > or =12(More)